Aporphine alkaloids, clerodane diterpenes, and other constituents from Tinospora cordifolia

Phan Van Kiem, Chau Van Minh, Nguyen Tien Dat, Lã Văn Kính, Dan Thuy Hang
Nguyen Hoai Nam, Nguyen Xuan Cuong, Hoang Thanh Huong, Trinh Van Lau

TÓM TẮT

Phytochemical investigation of the methanol extract of Tinospora cordifolia aerial parts led to the isolation of four new and seven known compounds. The structures of two new aporphine alkaloids, N-formylasimilobine 2-O-βD-glucopyranosyl-(1→2)-β-D-glucopyranoside (tinoscorside A, 1)andN-acetylasimilobine 2-O- βD-glucopyranosyl-(1→2)-β- D-glucopyranoside (tinoscorside B, 2), a new clerodane diterpene, tinoscorside C (3), and a new phenylpropanoid, sinapyl 4-O-βD-apiofuranosyl-(1→6)-O-β-D-glucopyranoside (tinoscorside D, 6) were determined by extensive spectroscopic methods including FTICR-MS and 1Dand 2DNMR.

Chi tiết 

Aporphine alkaloids, clerodane diterpenes, and other constituents from Tinospora cordifolia

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